Doing an Elizabeth

Coralie Fargeat’s The Substance inspired this Telegraph article about copies and clones

Hollywood has-been Elisabeth Sparkle didn’t look where she was going, and got badly shaken about in a traffic accident. Now she’s in the emergency room, and an unfeasibly handsome young male nurse is running his fingers down her spine. Nothing’s wrong. On the contrary: Elisabeth (played by Demi Moore) is, she’s told, “a perfect candidate”.

The next day she gets a box through the post. Inside is a kit that will enable her to duplicate herself. The instructions couldn’t be clearer. Even when fully separated, Elisabeth and the younger, better version of herself who’s just spilled amniotically out of her back (Sue, played by Margaret Qualley) are one. While one of them gets to play in the sun for a week, the other must lie in semi-coma, feeding off an intravenous drip. Each week, they swap roles.

Writer-director Coralie Fargeat’s script for The Substance is one of those super-lucid cinematic fun-rides that can’t help but put you in mind of other, admittedly rather better movies. In Joe Mankiewicz’s All About Eve (1950), an actress’s personal assistant plots to steal her career. In John Frankenheimer’s Seconds (1966), Rock Hudson gets his youth back and quickly learns to hate it. In David Cronenberg’s The Fly (1986) biologist Seth Brundle’s experiment in gene splicing is a none-too-subtle metaphor for the ageing process.

Recently, I ran into a biotechnology company called StoreGene. They sent me a blood sample kit in a little box and promised me a lifetime of personalised medicine, so long as I let them read my entire genetic code.

I’m older than Elisabeth Sparkle (sacked from her daytime TV fitness show on her 50th birthday) and a sight less fit than Demi Moore, and so I seized StoreGene’s offer with both palsied, liver-spotted hands.

Now, somewhere in what we call the Cloud (some anonymous data centre outside Chicago, more like) I have a double. Unlike Elizabeth’s Sue, though, my double won’t resent the fact that I am using him as a means. He is not going to flinch, or feel violated in any way, as his virtual self is put through trial after trial.

Every year, more than a million medical research papers are published. It’s impossible to know what this deluge of new discovery means to me personally – but now my GP can find out, at the push of a button, what it means for my genetic data-double.

Should I take this medicine, or that? Should I take more of it, or less of it? What treatment will work; what won’t? No more uncertainty for me: now I am guaranteed to receive treatments that are tailored to me, forever. I’ve just landed, bang, in the middle of a new era of personalised medicine.

Now that there’s a digital clone of me floating around, I have even less reason to want to “do an Elisabeth” and make a flesh-and-blood copy of myself. This will come as a relief to anyone who’s read Kazuo Ishiguro’s 2005 novel Never Let Me Go, and can’t shake off the horror occasioned by that school assembly: “If you’re going to have decent lives,” Miss Lucy tells the children in her care, “then you’ve got to know and know properly… You’ll become adults, then before you’re old, before you’re even middle-aged, you’ll start to donate your vital organs.”

Might we one day farm clones of ourselves to provide our ageing, misused bodies with spare parts? This is by far the best of the straw-man arguments that have been mounted over the years against the idea of human cloning. (Most of the others involve Hitler.)

It at least focuses our minds on a key ethical question: are we ever entitled to use other people as means to an end? But it’s still a straw-man argument, not least because we’re a long way into figuring out how to grow our spare organs in other animals. No ethical worries there! (though the pigs may disagree).

And while such xenotransplantation and other technologies advance by leaps and bounds, reproductive cloning languishes – a rather baroque solution to biomedical problems solved more easily by other means.

Famously, In 1996 Ian Wilmut and colleagues at the Roslin Institute in Scotland successfully cloned Dolly the sheep from the udder cells of a ewe. Dolly was their 277th attempt. She died young. No-one can really say whether this had anything to do with her being a clone, since her creation conspicuously did not open the floodgates to further experimentation. Two decades went by before the first primates were successfully cloned – two crab-eating macaques named Zhong Zhong and Hua Hua. These days it’s possible to clone your pet (Barbara Streisand famously cloned her dog), but my strong advice is, don’t bother: around 96 per cent of all cloning attempts end in failure.

Science-fiction stories, from Aldous Huxley’s Brave New World (1932) to Andrew Niccol’s Gattaca (1997), have conjured up hyper-utilitarian nightmares in which manipulations of the human genome work all too well. This is what made David Cronenberg’s early body horror so compelling and, in retrospect, so visionary: in films such as 1977’s Rabid (a biker develops a blood-sucking orifice) and 1979’s The Brood (ectopic pregnancies manifest a divorcée’s rage), the body doesn’t give a stuff about anyone’s PhD; it has its own ideas about what it wants to be.

And so it has proved. Not only does cloning rarely succeed; the clone that manages to survive to term will most likely be deformed, or die of cancer, or keel over for some other more or less mysterious reason. After cloning Dolly the sheep, Wilmut and his team tried to clone another lamb; it hyperventilated so much it kept passing out.

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It is conceivable, I suppose, that hundreds of years from now, alien intelligences will dust off StoreGene’s recording of my genome and, in a fit of misplaced enthusiasm, set about growing a copy of me in a modishly lit plexiglass tank. Much good may it do them: the clone they’re growing will bear only a passing physical resemblance to me, and he and I will share only the very broadest psychological and emotional similarity. Genes make a big contribution to the development process, but they’re not in overall charge of it. Even identical twins, nature’s own clones, are easy to tell apart, especially when they start speaking.

Call me naive, but I’m not too worried about vast and cool and unsympathetic intellects, alien or otherwise, getting hold of my genetic data. It’s the thought of what all my other data may be up to that keeps me up at night.

Swedish political scientist Carl Öhman’s The Afterlife of Data, published earlier this year, recounts the experiences of a young man who, having lost his father ten years previously, finds that they can still compete against each other on an old XBox racing game. That is, he can play against his father’s saved games, again and again. (Of course he’s now living in dread of the day the XBox eventually breaks and his dad dies a second time.)

The digital world has been part of our lives for most of our lives, if not all of them. We are each of us mirrored there. And there’s this in common between exploring digital technology and exploring the Moon: no wind will come along to blow away our footprints.

Öhman’s book is mostly an exploration of the unstable but fast-growing sector of “grieving technologies” which create – from our digital footprints – chatbots, which our grieving loved ones can interrogate on those long lonely winter evenings. Rather more uncanny, to my mind, are those chatbots of us that stalk the internet while we’re still alive, causing trouble on our behalf. How long will it be before my wife starts ringing me up out of the blue to ask me the PIN for our joint debit card?

Answer: in no time at all, at least according to a note on “human machine teaming” published six (six!) years ago by the Ministry of Defence. Its prediction that “forgeries are likely to constitute a large proportion of online content” was stuffily phrased, but accurate enough: in 2023 nearly half of all internet traffic came from bots.

At what point does a picture of yourself acquire its own reality? At what point does that picture’s existence start ruining your life? Oscar Wilde took a stab at what in 1891 must have seemed a very noodly question with his novel The Picture of Dorian Gray. 130-odd years later, Sarah Snook’s one-woman take on the story at London’s Haymarket Theatre employed digital beauty filters and mutiple screens in what felt less like an updating of Wilde’s story, more its apocalyptic restatement: all lives end, and a life wholly given over to the pursuit of beauty and pleasure is not going to end well.

In 2021, users of TikTok noticed that the platform’s default front-facing camera was slimming down their faces, smoothing their skin, whitening their teeth and altering the size of their eyes and noses. (You couldn’t disable this feature, either.) When you play with these apps, you begin to appreciate their uncanny pull. I remember the first time TikTok’s “Bold Glamour” filter, released last year, mapped itself over my image with an absolute seamlessness. Quite simply, a better me appeared in the phone’s digital mirror. When I gurned, it gurned. When I laughed, it laughed. It had me fixated for days and, for heaven’s sake, I’m a middle-aged bloke. Girls, you’re the target audience here. If you want to know what your better selves are up to, all you have to do is look into your smartphone.

Better yet, head to a clinic near you (while there are still appointments available), get your fill of fillers, and while your face is swelling like an Aardman Animations outtake, listen in as practitioners of variable experience and capacity talk glibly of “Zoom-face dysphoria”.
That this self-transfiguring trend has disfigured a generation is not really the worry. The Kardashian visage (tan by Baywatch, brows and eye shape by Bollywood, lips from Atlanta, cheeks from Pocahontas, nose from Gwyneth Paltrow) is a mostly non-surgical artefact – a hyaluronic-acid trip that will melt away in six months to a year, once people come to their senses. What really matters is that among school-age girls, rates of depression and self-harm are through the roof. I had a whale of a time at that screening of The Substance. But the terrifying reality is that the film isn’t for me; it’s for them.